{"id":5314,"date":"2022-10-23T15:31:00","date_gmt":"2022-10-23T14:31:00","guid":{"rendered":"https:\/\/catapult.org.uk\/?post_type=case_study&#038;p=5314"},"modified":"2023-08-21T12:28:17","modified_gmt":"2023-08-21T11:28:17","slug":"delivering-safer-advanced-therapies-faster-and-at-lower-cost-through-technology-and-process-innovation","status":"publish","type":"case_study","link":"https:\/\/catapult.org.uk\/our-work\/case-studies\/delivering-safer-advanced-therapies-faster-and-at-lower-cost-through-technology-and-process-innovation\/","title":{"rendered":"Delivering safer advanced therapies, faster and at lower cost through technology and process innovation"},"content":{"rendered":"\n<div style=\"height:54px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:10%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:90%\">\n<h1 class=\"wp-block-heading\">Delivering safer advanced therapies, faster and at lower cost through technology and process innovation<\/h1>\n\n\n\n<div style=\"height:54px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"684\" src=\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2022\/08\/CGTC-priorty-3TPI-2-1024x684.jpg\" alt=\"\" class=\"wp-image-5316\" srcset=\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2022\/08\/CGTC-priorty-3TPI-2-1024x684.jpg 1024w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2022\/08\/CGTC-priorty-3TPI-2-300x200.jpg 300w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2022\/08\/CGTC-priorty-3TPI-2-768x513.jpg 768w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2022\/08\/CGTC-priorty-3TPI-2-1536x1026.jpg 1536w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2022\/08\/CGTC-priorty-3TPI-2-2048x1368.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n<div style=\"height:0px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div\n  class=\"mt-5 mb-5 blockQuote  position-relative\"\n  style=\"padding-left: 40px;border-left: solid #393D48 10px;\">\n    <svg class=\"pb-3\" width=\"26\" height=\"40\" viewBox=\"0 0 20 17\"\n    style=\"fill-rule:evenodd;clip-rule:evenodd;stroke-linejoin:round;stroke-miterlimit:2;\">\n    <path\n      d=\"M2.173,0l-2.173,7.704l0,8.796l8.15,0l-0,-8.667l-2.415,-0l1.328,-7.833l-4.89,0Zm11.35,0l-2.173,7.704l0,8.796l8.15,0l0,-8.667l-2.415,-0l1.329,-7.833l-4.891,0Z\"\n      style=\"fill:#FE5000;fill-rule:nonzero;\" \/>\n  <\/svg>\n      <p class=\"quoteContent\" style=\"color:black;\">\n    <em>One of the things which really pleased me about this collaboration was their shared excitement around our ground-breaking technology. Importantly we were able to access a diverse range of expertise that probably isn\u2019t available elsewhere. The Catapult interaction has gone way beyond the input originally envisaged. The support we have received from the team at Cell and Gene Therapy Catapult has been nothing short of fantastic.<\/em>  <\/p>\n  \n    <div class=\"quoteFooterContent pt-3 pb-3\"\n    style=\"font-size: 1.125rem; color: black;\">\n    <strong>Andrew Wilson <\/strong><br>Senior Research Commercialisation Manager at the University of Bristol  <\/div>\n  \n  \n    <div class=\"text-right\">\n    <svg width=\"26\" height=\"40\" viewBox=\"0 0 20 17\"\n      style=\"fill-rule:evenodd;clip-rule:evenodd;stroke-linejoin:round;stroke-miterlimit:2;\">\n      <path\n        d=\"M17.464,16.594l2.19,-7.748l-0,-8.846l-8.214,0l-0,8.716l2.434,0l-1.339,7.878l4.929,-0Zm-11.44,-0l2.19,-7.748l0,-8.846l-8.214,0l0,8.716l2.434,0l-1.339,7.878l4.929,-0Z\"\n        style=\"fill:#FE5000;fill-rule:nonzero;\" \/>\n    <\/svg>\n  <\/div>\n  <\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>At its core, Cell and Gene Therapy Catapult is an innovation and technology company. Its work with industry in the development of novel processes and analytical techniques for cell and gene therapy manufacture has supported significant investment into startup businesses as well as attracting international manufacturers such as Rentschler to invest in manufacturing in the UK.<\/p>\n\n\n\n<p>The Catapult is committed to ensuring the UK can effectively turn academic research into advanced therapy medicinal products (ATMP).<\/p>\n\n\n\n<p>In 2015 a programme was launched to establish national capability in Adeno Associated Viruses (AAV),which has led to more investment,the creation of spin-out companies and therapy developers employing Catapult developed technology.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>The Cell and Gene Therapy Catapult helped researchers in Bristol secure Series A funding investment of \u00a345 million to create PureSpring Therapeutics, one of the largest single investments made to a UK university biotech spin-out.<\/p>\n\n\n\n<p>In addition, work was carried out in Bioprocessing systems innovation to develop manufacturing process controls and automated manufacturing systems to detect and correct variances in batch performance, reducing patient to patient and\/or batch to batch variation \u2013 delivering ATMP production at high quality with lower cost.<\/p>\n\n\n\n<p>The team has gone on to form a Process Analytical Technology Consortium of 24 national and international companies which will extend the work to deliver even greater value, productivity and patient safety.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:0px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:0px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div style=\"background-color: white;background:\"\n                    class=\"pt-5 pb-5  alignwide\"\n                >    <div class=\"container impactGrid\">        <div class=\"row\">            <div class=\"col-md-6 border-top-dashed border-bottom-sm-dashed border-right-sm-dashed pl-0 pr-0 pt-4 pb-4 d-flex align-items-center\"\n                                style=\"border-color:#FE5000;color:#FE5000;\"\n                            >                    <div class=\"col-md-8 d-flex flex-column justify-content-center\">                        <span class=\"figure\"\n                                            style=\"font-size:2.8125rem\"\n                                        >\n                                            \u00a345m\n                                        <\/span>\n\n                                        <br\/>\n\n                                        <div class=\"raleway font-weight-bold\">\n                                            of investment to create  Purespring Therapeutic\n                                        <\/div>\n\n                                    <\/div>\n\n                                    <div class=\"col-4 col-sm-2 col-md-4 d-flex justify-content-center\"><img loading=\"lazy\" decoding=\"async\" width=\"70\" height=\"70\" class=\"img-fluid\" style=\"object-fit:contain\" src=\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/12\/coins-solid.svg\">                    <\/div>\n\n                            <\/div>            <div class=\"col-md-6 border-top-dashed border-bottom-dashed pr-0 pl-0 pt-4 pb-4 d-flex align-items-center\"\n                                style=\"border-color:#FE5000;color:#FE5000;\"\n                            >                    <div class=\"col-md-8 d-flex flex-column justify-content-center\">                        <span class=\"figure\"\n                                            style=\"font-size:2.8125rem\"\n                                        >\n                                            24\n                                        <\/span>\n\n                                        <br\/>\n\n                                        <div class=\"raleway font-weight-bold\">\n                                            companies in dedicated consortium\n                                        <\/div>                    <\/div>\n\n                                    <div class=\"col-4 col-sm-2 col-md-4 d-flex justify-content-center\">                            <img loading=\"lazy\" decoding=\"async\" width=\"70\" height=\"70\" class=\"img-fluid\" style=\"object-fit:contain\" src=\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/12\/dna-solid.svg\">                    <\/div>\n\n                            <\/div>\n\n                        <\/div>    <\/div>\n\n                <\/div>\n\n\n<div style=\"height:0px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-large is-style-rounded\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2021\/07\/University_of_Bristol-CGTC-1024x683.jpg\" alt=\"\" class=\"wp-image-3523\" srcset=\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2021\/07\/University_of_Bristol-CGTC-1024x683.jpg 1024w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2021\/07\/University_of_Bristol-CGTC-300x200.jpg 300w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2021\/07\/University_of_Bristol-CGTC-768x512.jpg 768w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2021\/07\/University_of_Bristol-CGTC-1536x1024.jpg 1536w, https:\/\/catapult.org.uk\/wp-content\/uploads\/2021\/07\/University_of_Bristol-CGTC-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:10%\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow 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Its work with industry in the development of novel processes and analytical techniques for cell and gene therapy manufacture has supported significant investment into startup businesses as well as attracting international manufacturers such as Rentschler to invest in manufacturing in the UK.<\/p>\n","protected":false},"featured_media":5316,"template":"","meta":{"_external_link_checkbox":false,"_external_link":"","_event_date":"","_featured_case_study":false},"categories":[9],"tags":[61,63],"class_list":["post-5314","case_study","type-case_study","status-publish","has-post-thumbnail","hentry","category-cell-and-gene-therapy","tag-catapult-highlights","tag-leverage"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Delivering safer advanced therapies, faster and at lower cost through technology and process innovation - The Catapult Network<\/title>\n<meta name=\"description\" content=\"At its core, Cell and Gene Therapy Catapult is an innovation and technology company. 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