{"id":696,"date":"2020-11-30T20:42:46","date_gmt":"2020-11-30T20:42:46","guid":{"rendered":"http:\/\/crosscatapultn.wpengine.com\/?post_type=case_study&p=696"},"modified":"2021-07-09T14:37:15","modified_gmt":"2021-07-09T13:37:15","slug":"enabling-the-development-of-potentially-life-saving-therapies","status":"publish","type":"case_study","link":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/","title":{"rendered":"Enabling the development of potentially life-saving therapies"},"content":{"rendered":"
\n\n
CASE STUDY<\/span>

Enabling the development of potentially life-saving therapies<\/h2> <\/div>

The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.<\/p> <\/div> <\/div>\n \n

\n
\n \n <\/div>\n <\/div> <\/div>\n\n <\/div>\n\n\n
<\/div>\n\n\n\n
\n
\n 2017\n <\/span>\n\n \n\n
\n Growth of SME: Asymptote was acquired by GE Healthcare in 2017\n <\/div> <\/div>\n\n
<\/div>\n\n <\/div>
\n \n <\/span>\n\n \n\n
\n Development of a whole product range of cell and gene therapies\n <\/div> <\/div>\n\n
<\/div>\n\n <\/div>
\n 2020\n <\/span>\n\n \n\n
\n First cell therapy liquid nitrogen-free cryogenic shipment system launched\n <\/div> <\/div>\n\n
<\/div> \n\n <\/div>
\n \n <\/span>\n\n \n\n
\n Enabled first had input from clinical centres to drive development\n <\/div> <\/div>\n\n
<\/div>\n\n <\/div>\n\n <\/div> \n\n <\/div><\/div>\n\n\n\n
\n
<\/div>\n\n\n\n \n \n <\/svg>\n

\n Asymptote Ltd has found the access to the NHS and ATMP developers through the ATTC network invaluable. Being part of this collaborative network has dramatically accelerated the development of Asymptote\u2019s technologies<\/em> <\/p>\n \n

\n John Morris Chief Executive Officer<\/strong>
Asymptote, part of Cytiva <\/div>\n \n \n
\n \n \n <\/svg>\n <\/div>\n <\/div>\n<\/div>\n<\/div>\n\n\n\n
\n
\n

Accelerating the development of technologies in cold chain management<\/h2>\n\n\n\n
<\/div>\n\n\n\n

The Cell and Gene Therapy Catapult approached Asymptote (now part of GE Healthcare) to apply its expertise in cryochain technology to develop a benchtop thawing device for the cryopreservation and delivery of cell and gene therapies.<\/p>\n\n\n\n

Maintaining cell quality throughout the manufacture and transportation of these treatments is a major challenge. The process is often carried out in water baths across multiple sites, with inconsistencies due to a subjective determination of the thaw endpoint as well as the risk of water-borne contamination. Cell thawing is the final and least controlled part of the chryogenic cold chain management. <\/p>\n\n\n\n

The collection and collation of data from thaw sites, often by paper records, also impedes therapy development. The final delivery, thaw and administration of these often-fragile therapies is therefore a crucial step, to ensure maximum therapeutic effect for the patient.<\/p>\n<\/div>\n\n\n\n

\n
\"\"<\/figure><\/div>\n\n\n\n

<\/p>\n<\/div>\n<\/div>\n\n\n\n

In partnership with Asymptote, two different prototypes were developed. The Catapult helped to make the technology suitable for cell and gene therapy workflows, generated IP, and provided market expertise, whilst Asymptote contributed its capabilities in engineering and design.<\/p>\n\n\n\n

The subsequent acquisition of Asymptote by GE Healthcare in 2017 enabled Asymptote to significantly scale-up product development and reach a larger market. GE Asymptote\u2019s Chronicle\u2122 software was used to capture data generated at different points, standardising the process and managing documentation<\/p>\n\n\n\n

GE Healthcare was renamed Cytiva in April 2020 following its acquisition by Danaher corporation. Cytiva launched the first liquid nitrogen-free cryogenic shipment system designed specifically for cell therapies in May 2020.<\/p>\n\n\n\n

<\/div>\n\n\n
\n\n
\n\n
\n

MORE CASE STUDIES<\/h2>\n <\/div>
\n \n
Highlights<\/div>
\n \n <\/div>\n \n <\/div>\n \n
\n \n
\n
CASE STUDY<\/div>\n
The Psychiatry Consortium – exploring new treatments for mental health conditions<\/div>\n
Medicines discovery for challenging diseases requires a collaborative approach with a patient focus. In 2019 the Medicines Discovery Catapult established the Psychiatry Consortium as one of its patient focussed partnerships. It is a strategic collaboration of two leading medical research charities and seven international pharmaceutical companies, focusing on the unmet therapeutic needs of people living with mental health conditions.<\/div>\n <\/div>\n \n
\n \n <\/div>\n \n <\/div>\n \n <\/div>\n \n <\/a>\n \n <\/div>
\n \n
Skills<\/div>
\n \n <\/div>\n \n <\/div>\n \n
\n \n
\n
CASE STUDY<\/div>\n
Addressing a market failure by providing real-world offshore wind demonstration opportunities<\/div>\n
The Offshore Renewable Energy Catapult has transformed the 7MW Levenmouth Demonstration Turbine (LDT) into the world\u2019s most advanced, open-access offshore wind turbine dedicated to research and development and a unique test and demonstration asset.<\/div>\n <\/div>\n \n
\n \n <\/div>\n \n <\/div>\n \n <\/div>\n \n <\/a>\n \n <\/div> <\/div>\n\n <\/div>\n\n <\/div>","protected":false},"excerpt":{"rendered":"

The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.<\/p>\n","protected":false},"featured_media":697,"template":"","meta":{"_external_link_checkbox":false,"_external_link":"","_event_date":"","_featured_case_study":false},"categories":[9],"tags":[15,16],"class_list":["post-696","case_study","type-case_study","status-publish","has-post-thumbnail","hentry","category-cell-and-gene-therapy","tag-modernising-health","tag-accelerating-business-growth"],"yoast_head":"\nEnabling the development of potentially life-saving therapies - The Catapult Network<\/title>\n<meta name=\"description\" content=\"The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Enabling the development of potentially life-saving therapies - The Catapult Network\" \/>\n<meta property=\"og:description\" content=\"The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/\" \/>\n<meta property=\"og:site_name\" content=\"The Catapult Network\" \/>\n<meta property=\"article:modified_time\" content=\"2021-07-09T13:37:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png\" \/>\n\t<meta property=\"og:image:width\" content=\"630\" \/>\n\t<meta property=\"og:image:height\" content=\"420\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Catapult_UK\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/\",\"url\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/\",\"name\":\"Enabling the development of potentially life-saving therapies - The Catapult Network\",\"isPartOf\":{\"@id\":\"https:\/\/catapult.org.uk\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png\",\"datePublished\":\"2020-11-30T20:42:46+00:00\",\"dateModified\":\"2021-07-09T13:37:15+00:00\",\"description\":\"The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.\",\"breadcrumb\":{\"@id\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#primaryimage\",\"url\":\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png\",\"contentUrl\":\"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png\",\"width\":\"630\",\"height\":\"420\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/catapult.org.uk\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Case Studies\",\"item\":\"https:\/\/catapult.org.uk\/our-work\/case-studies\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Enabling the development of potentially life-saving therapies\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/catapult.org.uk\/#website\",\"url\":\"https:\/\/catapult.org.uk\/\",\"name\":\"The Catapult Network\",\"description\":\"The Innovate UK Catapult Network\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/catapult.org.uk\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Enabling the development of potentially life-saving therapies - The Catapult Network","description":"The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/","og_locale":"en_GB","og_type":"article","og_title":"Enabling the development of potentially life-saving therapies - The Catapult Network","og_description":"The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.","og_url":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/","og_site_name":"The Catapult Network","article_modified_time":"2021-07-09T13:37:15+00:00","og_image":[{"width":630,"height":420,"url":"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@Catapult_UK","twitter_misc":{"Estimated reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/","url":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/","name":"Enabling the development of potentially life-saving therapies - The Catapult Network","isPartOf":{"@id":"https:\/\/catapult.org.uk\/#website"},"primaryImageOfPage":{"@id":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#primaryimage"},"image":{"@id":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#primaryimage"},"thumbnailUrl":"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png","datePublished":"2020-11-30T20:42:46+00:00","dateModified":"2021-07-09T13:37:15+00:00","description":"The emergence of cell therapies will potentially change the landscape of healthcare. The Cell and Gene Therapy Catapult, identified the need for a cell thawing system that would reduce barriers to the commercialisation.","breadcrumb":{"@id":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#primaryimage","url":"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png","contentUrl":"https:\/\/catapult.org.uk\/wp-content\/uploads\/2020\/11\/catapult-CGTC-casestudies-Enabling-the-development-of-potentially-life-saving-therapies-4-Dec-2020-side01.png","width":"630","height":"420"},{"@type":"BreadcrumbList","@id":"https:\/\/catapult.org.uk\/our-work\/case-studies\/enabling-the-development-of-potentially-life-saving-therapies\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/catapult.org.uk\/"},{"@type":"ListItem","position":2,"name":"Case Studies","item":"https:\/\/catapult.org.uk\/our-work\/case-studies\/"},{"@type":"ListItem","position":3,"name":"Enabling the development of potentially life-saving therapies"}]},{"@type":"WebSite","@id":"https:\/\/catapult.org.uk\/#website","url":"https:\/\/catapult.org.uk\/","name":"The Catapult Network","description":"The Innovate UK Catapult Network","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/catapult.org.uk\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"}]}},"_links":{"self":[{"href":"https:\/\/catapult.org.uk\/wp-json\/wp\/v2\/case_study\/696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/catapult.org.uk\/wp-json\/wp\/v2\/case_study"}],"about":[{"href":"https:\/\/catapult.org.uk\/wp-json\/wp\/v2\/types\/case_study"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/catapult.org.uk\/wp-json\/wp\/v2\/media\/697"}],"wp:attachment":[{"href":"https:\/\/catapult.org.uk\/wp-json\/wp\/v2\/media?parent=696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/catapult.org.uk\/wp-json\/wp\/v2\/categories?post=696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/catapult.org.uk\/wp-json\/wp\/v2\/tags?post=696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}